National Cancer Institute “Cancer Moonshot Biobank”

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NCT#:NCT04314401
NCT QR Code
Title:National Cancer Institute “Cancer Moonshot Biobank”
Protocol:Moonshot
Cancer Type: Multiple cancer types:
Colorectal cancer: Stage IV;
Non-small cell or small cell lung cancer: Stage III/IV;
Prostate cancer: metastatic prostate cancer;
Gastric cancer, NOS: Stage IV;
Esophageal cancer, NOS: Stage IV;
Adenocarcinoma of gastroesophageal junction: Stage IV;
High Grade Serous ovarian cancer: Stage III/IV;
Invasive breast carcinoma: Stage III/IV;
Melanoma: Stage III/IV;
Acute myeloid leukemia;
Multiple myeloma.
Study Sponsor: National Cancer Institute (NCI)
Brief Summary:  This trial collects multiple tissue and blood samples, along with medical information, from cancer patients. The “Cancer Moonshot Biobank” is a longitudinal study. This means it collects and stores samples and information over time, throughout the course of a patient’s cancer treatment. By looking at samples and information collected from the same people over time, researchers hope to better understand how cancer changes over time and over the course of medical treatments.
Study Type: Observational
Date Opened at SVMHS:  January 24, 2025
Recruitment Status:  Recruiting
Study Population:   13 Years and older (Child,  Adult,  Older Adult)
Eligibility Criteria: Diagnosed with one of the following: Colorectal cancer: stage IV, Non-small cell or small cell lung cancer: stage III/IV, Prostate cancer: metastatic prostate cancer, Gastric cancer, not otherwise specified (NOS): stage IV, Esophageal cancer, NOS: stage IV, Adenocarcinoma of gastroesophageal junction: stage IV, High grade serous ovarian cancer: stage III/IV, Invasive breast carcinoma: stage III/IV, Melanoma: stage III/IV, Acute myeloid leukemia, Multiple myeloma
Principal Investigator:  Geetha N. Varma, MD, Oncology, Salinas Valley Health Cancer Care, (831) 755-1701
Participating Institution:  Salinas Valley Memorial Healthcare System & Salinas Valley Medical Clinics & Salinas Valley Memorial Hospital
SVMHS Clinical Research Program:  Terri Nielsen, MSJ, RN, CCRP, Clinical Research Program Manager, tnielsen2@svmh.com
Link to ClinicalTrials.gov:  https://clinicaltrials.gov/study/NCT04314401?cond=moonshot&rank=1#study-overview

International Registry for Men With Advanced Prostate Cancer (IRONMAN) (IRONMAN)

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NCT#: & LinkNCT03151629
NCT QR Code
Available as of:July 15, 2024
Contract:Caris
Indication Category:Prostate
Study Sponsor:PCCTC
Protocol #:PRODIGY
Title:International Registry for Men With Advanced Prostate Cancer (IRONMAN) (IRONMAN)
Highlight Details:IRONMAN Registry Sub-Study: PRODIGY: Observational study to describe effectiveness of olaparib in subjects with metastatic castration-resistant prostate cancer who have failed prior treatment with a new hormonal agent and carry selected homologous recombination repair gene mutations 
Biomarkers:HRR mutations (BARD1, BRIP1, CHEK1, FANCL, PALB2, RAD51B, RAD51C, RAD51D, and RAD54L)
Indication:Prostate (mCRPC) 
Phase:
Treatment Line:
Study Drug/Test Compound:
Notes
Recruitment Status:Just In Time
Participating Institution:Salinas Valley Health
Salinas Valley Health Clinical Research Program:Terri Nielsen, MSJ, RN, CCRP, Clinical Research Program Manager, research@salinasvalleyhealth.com